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BDBM50223602 CHEMBL442802::N-(2-(5-phenyl-7-(pyridin-3-ylmethylamino)pyrazolo[1,5-a]pyrimidin-3-ylthio)ethyl)acetamide

SMILES: CC(=O)NCCSc1cnn2c(NCc3cccnc3)cc(nc12)-c1ccccc1

InChI Key: InChIKey=FBEATWYWJRBSSB-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223602   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM50223602
PNG
(CHEMBL442802 | N-(2-(5-phenyl-7-(pyridin-3-ylmethy...)
Show SMILES CC(=O)NCCSc1cnn2c(NCc3cccnc3)cc(nc12)-c1ccccc1
Show InChI InChI=1S/C22H22N6OS/c1-16(29)24-10-11-30-20-15-26-28-21(25-14-17-6-5-9-23-13-17)12-19(27-22(20)28)18-7-3-2-4-8-18/h2-9,12-13,15,25H,10-11,14H2,1H3,(H,24,29)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 34n/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human GSK3beta


Bioorg Med Chem Lett 17: 6220-3 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.017
BindingDB Entry DOI: 10.7270/Q27M07ND
More data for this
Ligand-Target Pair