BDBM50224182 (R)-1-(4-(2-((S)-1-amino-2-methylpropyl)-4-methylphenyl)piperazin-1-yl)-3-(4-chlorophenyl)-2-methylpropan-1-one::1-{2-[(1S)-amino-2-methylpropyl]-4-methylphenyl}-4-[(2R)-methyl-3-(4-chlorophenyl)propionyl]piperazine::CHEMBL401250
SMILES CC(C)[C@H](N)c1cc(C)ccc1N1CCN(CC1)C(=O)[C@H](C)Cc1ccc(Cl)cc1
InChI Key InChIKey=IMYWIXVEAKDSQK-DVECYGJZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50224182
Affinity DataKi: 69nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 69nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Antagonist activity at human MC4R expressed in CHO cells assessed as inhibition of alpha-MSH-induced cAMP production by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Antagonist activity at MC4R assessed as inhibition of alpha-MSH-stimulated cAMP releaseMore data for this Ligand-Target Pair