BDBM50224389 8-(4-methylphenyl)-2-(methylthio)thiazolo[4'',5'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-7(8H)-one::CHEMBL235767
SMILES CSc1nc2c(cnc3sc4c(ncn(-c5ccc(C)cc5)c4=O)c23)s1
InChI Key InChIKey=MIHOPTCNVPPWSH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50224389
Affinity DataKi: 788nMAssay Description:Displacement of [3H]9-Dimethylamino-3-(4-methoxy-phenyl)-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one from mGluR1 in rat cerebellum membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 636nMAssay Description:Antagonist activity at human mGluR1a expressed in CHO cells assessed by measuring intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair