BDBM50224719 CHEMBL391354::benzyl 4-((5-chloro-2-(1-(2-(3-oxo-2,3-dihydrobenzo[b][1,4]oxazin-4-yl)ethyl)piperidin-4-yl)benzamido)methyl)piperidine-1-carboxylate

SMILES Clc1ccc(C2CCN(CCN3C(=O)COc4ccccc34)CC2)c(c1)C(=O)NCC1CCN(CC1)C(=O)OCc1ccccc1

InChI Key InChIKey=OPEGMUOHWDCNGL-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50224719   

TargetUrotensin-2 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50224719(CHEMBL391354 | benzyl 4-((5-chloro-2-(1-(2-(3-oxo-...)
Affinity DataKi:  54nMAssay Description:Displacement of [125I]U2 from human UT receptor in RMS13 cells after 2.5 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrotensin-2 receptor(RAT)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50224719(CHEMBL391354 | benzyl 4-((5-chloro-2-(1-(2-(3-oxo-...)
Affinity DataIC50:  400nMAssay Description:Antagonist activity at rat UT receptor transfected in CHOK1 cells assessed as calcium mobilization by FLIPR methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed