BDBM50224759 (2R,3R,4S,5R)-2-(2-chloro-6-((R)-tetrahydrofuran-3-ylamino)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol::CHEMBL252198

SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N[C@@H]3CCOC3)nc(Cl)nc12

InChI Key InChIKey=XEAJNSCYKKKRRS-KWGHVAAJSA-N

Data  7 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50224759   

TargetAdenosine receptor A1(BOVINE)
Universit£

Curated by ChEMBL
LigandPNGBDBM50224759((2R,3R,4S,5R)-2-(2-chloro-6-((R)-tetrahydrofuran-3...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in bovine cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224759((2R,3R,4S,5R)-2-(2-chloro-6-((R)-tetrahydrofuran-3...)
Affinity DataKi:  1.87nMAssay Description:Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
Universit£

Curated by ChEMBL
LigandPNGBDBM50224759((2R,3R,4S,5R)-2-(2-chloro-6-((R)-tetrahydrofuran-3...)
Affinity DataKi:  6.60nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in pig cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224759((2R,3R,4S,5R)-2-(2-chloro-6-((R)-tetrahydrofuran-3...)
Affinity DataKi:  211nMAssay Description:Agonist activity at human recombinant adenosine A2B receptor expressed in CHO cells assessed as activation of adenylyl cyclase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224759((2R,3R,4S,5R)-2-(2-chloro-6-((R)-tetrahydrofuran-3...)
Affinity DataKi:  4.59E+3nMAssay Description:Displacement of [3H]NECA from human recombinant adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(BOVINE)
Universit£

Curated by ChEMBL
LigandPNGBDBM50224759((2R,3R,4S,5R)-2-(2-chloro-6-((R)-tetrahydrofuran-3...)
Affinity DataKi:  4.69E+3nMAssay Description:Displacement of [3H]CGS21680 from adenosine A1 receptor in bovine striatum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224759((2R,3R,4S,5R)-2-(2-chloro-6-((R)-tetrahydrofuran-3...)
Affinity DataKi:  3.46E+4nMAssay Description:Displacement of [3H]NECA from human recombinant adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
Universit£

Curated by ChEMBL
LigandPNGBDBM50224759((2R,3R,4S,5R)-2-(2-chloro-6-((R)-tetrahydrofuran-3...)
Affinity DataEC50:  18.3nMAssay Description:Agonist activity at adenosine A1 receptor in pig cortical membrane assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed