BDBM50225096 1-(7-aza-bicyclo[2.2.1]heptan-7-yl)-2-(5-(3,5-dimethylphenyl)-4-(2-(3-methyl-4-(morpholine-4-carbonyl)piperidin-1-yl)ethyl)-6H-thieno[2,3-b]pyrrol-2-yl)-2-methylpropan-1-one::CHEMBL399857

SMILES CC1CN(CCc2c([nH]c3sc(cc23)C(C)(C)C(=O)N2C3CCC2CC3)-c2cc(C)cc(C)c2)CCC1C(=O)N1CCOCC1

InChI Key InChIKey=ATYOFXVORANGGC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50225096   

TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50225096(1-(7-aza-bicyclo[2.2.1]heptan-7-yl)-2-(5-(3,5-dime...)
Affinity DataIC50:  88nMAssay Description:Displacement of [125I]D-Trp from human GnRH receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50225096(1-(7-aza-bicyclo[2.2.1]heptan-7-yl)-2-(5-(3,5-dime...)
Affinity DataIC50:  43nMAssay Description:Displacement of [125I]D-Trp from rat GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50225096(1-(7-aza-bicyclo[2.2.1]heptan-7-yl)-2-(5-(3,5-dime...)
Affinity DataIC50:  220nMAssay Description:Antagonist activity at GnRH receptor expressed in AP Han Wistar rat primary pitutary cells assessed as inhibition of GnRH stimulated LH release after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed