BDBM50225437 (2S,3R)-2-amino-1-(isoindolin-2-yl)-3-methylpentan-1-one::CHEMBL397070

SMILES CC[C@@H](C)[C@H](N)C(=O)N1Cc2ccccc2C1

InChI Key InChIKey=UBDCHKXSBGAGNJ-MFKMUULPSA-N

Data  21 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 50225437   

TargetDipeptidyl peptidase 2(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50225437((2S,3R)-2-amino-1-(isoindolin-2-yl)-3-methylpentan...)
Affinity DataIC50:  2.87E+4nMAssay Description:Inhibition of human DPP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM50225437((2S,3R)-2-amino-1-(isoindolin-2-yl)-3-methylpentan...)
Affinity DataIC50:  120nMAssay Description:Inhibition of DPP8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50225437((2S,3R)-2-amino-1-(isoindolin-2-yl)-3-methylpentan...)
Affinity DataIC50:  9.00E+4nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50225437((2S,3R)-2-amino-1-(isoindolin-2-yl)-3-methylpentan...)
Affinity DataIC50:  9.00E+4nMAssay Description:Inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50225437((2S,3R)-2-amino-1-(isoindolin-2-yl)-3-methylpentan...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of DPP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50225437((2S,3R)-2-amino-1-(isoindolin-2-yl)-3-methylpentan...)
Affinity DataIC50:  9.00E+4nMAssay Description:Inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50225437((2S,3R)-2-amino-1-(isoindolin-2-yl)-3-methylpentan...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of DPP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM50225437((2S,3R)-2-amino-1-(isoindolin-2-yl)-3-methylpentan...)
Affinity DataIC50:  120nMAssay Description:Inhibition of DPP8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50225437((2S,3R)-2-amino-1-(isoindolin-2-yl)-3-methylpentan...)
Affinity DataIC50:  290nMAssay Description:Inhibition of DPP9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50225437((2S,3R)-2-amino-1-(isoindolin-2-yl)-3-methylpentan...)
Affinity DataIC50:  290nMAssay Description:Inhibition of DPP9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM50225437((2S,3R)-2-amino-1-(isoindolin-2-yl)-3-methylpentan...)
Affinity DataIC50:  120nMAssay Description:Inhibition of DPP8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50225437((2S,3R)-2-amino-1-(isoindolin-2-yl)-3-methylpentan...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant FAP expressed in Hi5 insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM50225437((2S,3R)-2-amino-1-(isoindolin-2-yl)-3-methylpentan...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human recombinant His-tagged DPP8 expressed in insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50225437((2S,3R)-2-amino-1-(isoindolin-2-yl)-3-methylpentan...)
Affinity DataIC50:  240nMAssay Description:Inhibition of human recombinant His-tagged DPP9 expressed in insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50225437((2S,3R)-2-amino-1-(isoindolin-2-yl)-3-methylpentan...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant His-tagged DPP2 expressed in insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50225437((2S,3R)-2-amino-1-(isoindolin-2-yl)-3-methylpentan...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant His-tagged DPP4 expressed in insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Bos taurus)
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM50225437((2S,3R)-2-amino-1-(isoindolin-2-yl)-3-methylpentan...)
Affinity DataIC50:  290nMAssay Description:Inhibition of bovine DPP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase IV(Porphyromonas gingivalis)
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM50225437((2S,3R)-2-amino-1-(isoindolin-2-yl)-3-methylpentan...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Porphyromonas gingivalis N-terminal His-tagged DPP4 expressed in Escherichia coli using Gly-Pro-p-nitroanilide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50225437((2S,3R)-2-amino-1-(isoindolin-2-yl)-3-methylpentan...)
Affinity DataIC50:  9.00E+4nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50225437((2S,3R)-2-amino-1-(isoindolin-2-yl)-3-methylpentan...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of DPP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM50225437((2S,3R)-2-amino-1-(isoindolin-2-yl)-3-methylpentan...)
Affinity DataIC50:  122nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed