BDBM50225898 (2-Methoxy-benzyl)-((2S,3S,3aR,6aS)-2-phenyl-octahydro-cyclopenta[b]pyrrol-3-yl)-amine::(2S,3S,3aR,6aS)-N-(2-methoxybenzyl)-2-phenyl-octahydrocyclopenta[b]pyrrol-3-amine::CHEMBL55591

SMILES COc1ccccc1CN[C@H]1[C@@H]2CCC[C@@H]2N[C@H]1c1ccccc1

InChI Key InChIKey=NDMOYPJHBNNRIM-ZFMNYDKASA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50225898   

TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50225898((2-Methoxy-benzyl)-((2S,3S,3aR,6aS)-2-phenyl-octah...)
Affinity DataKi:  2.40nMAssay Description:In vitro binding affinity of the compound towards human NK-1 receptor in IM-9 cells using [3H]-SP of substance P antagonistMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50225898((2-Methoxy-benzyl)-((2S,3S,3aR,6aS)-2-phenyl-octah...)
Affinity DataIC50:  2.40nMAssay Description:Binding affinity was measured against the Tachykinin receptor 1 in human IM-9 cells using [3H]SP as ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50225898((2-Methoxy-benzyl)-((2S,3S,3aR,6aS)-2-phenyl-octah...)
Affinity DataIC50:  3.40nMAssay Description:Displacement of [3H]substance P from NK1 human receptor expressed in IM9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed