BDBM50226008 (R)-3-(4-propylmorpholin-2-yl)phenol::CHEMBL250403

SMILES CCCN1CCO[C@@H](C1)c1cccc(O)c1

InChI Key InChIKey=WYEGTIGJSHGEID-UHFFFAOYSA-N

Data  6 KI  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50226008   

TargetD(3) dopamine receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226008((R)-3-(4-propylmorpholin-2-yl)phenol | CHEMBL25040...)
Affinity DataEC50:  8nMAssay Description:Agonist activity at human recombinant dopamine D3 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226008((R)-3-(4-propylmorpholin-2-yl)phenol | CHEMBL25040...)
Affinity DataKi:  970nMAssay Description:Binding affinity to rat 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226008((R)-3-(4-propylmorpholin-2-yl)phenol | CHEMBL25040...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to human muscarinic M1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226008((R)-3-(4-propylmorpholin-2-yl)phenol | CHEMBL25040...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to human alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226008((R)-3-(4-propylmorpholin-2-yl)phenol | CHEMBL25040...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to rat alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226008((R)-3-(4-propylmorpholin-2-yl)phenol | CHEMBL25040...)
Affinity DataKi: >2.00E+3nMAssay Description:Binding affinity to human histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
LigandPNGBDBM50226008((R)-3-(4-propylmorpholin-2-yl)phenol | CHEMBL25040...)
Affinity DataKi: >4.00E+3nMAssay Description:Displacement of dofetilide from hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226008((R)-3-(4-propylmorpholin-2-yl)phenol | CHEMBL25040...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to dopamine D1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226008((R)-3-(4-propylmorpholin-2-yl)phenol | CHEMBL25040...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant dopamine D2 receptor expressed in rat pituitary cells assessed as inhibition of forskolin-stimulated cAMP accum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226008((R)-3-(4-propylmorpholin-2-yl)phenol | CHEMBL25040...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to dopamine D5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226008((R)-3-(4-propylmorpholin-2-yl)phenol | CHEMBL25040...)
Affinity DataIC50: 2.00E+4nMAssay Description:Antagonist activity at human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed