BDBM50226181 (3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-3-(3-methylbut-2-enyl)benzamido)-2-oxo-2H-chromen-7-yloxy)-3-methoxy-2,2-dimethyl-tetrahydro-2H-pyran-4-yl carbamate::(3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-3-(3-methylbut-2-enyl)benzamido)-8-methyl-2-oxo-2H-chromen-7-yloxy)-3-methoxy-2,2-dimethyl-tetrahydro-2H-pyran-4-yl carbamate::CHEMBL36506::Carbamic acid (3R,4S,5R,6R)-5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-3-(3-methyl-but-2-enyl)-benzoylamino]-8-methyl-2-oxo-2H-chromen-7-yloxy}-3-methoxy-2,2-dimethyl-tetrahydro-pyran-4-yl ester::Carbamic acid (3R,4S,5R,6R)-5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-3-(4-methyl-pent-3-enyl)-benzoylamino]-8-methyl-2-oxo-2H-chromen-7-yloxy}-3-methoxy-2,2-dimethyl-tetrahydro-pyran-4-yl ester::Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-3-(3-methyl-but-2-enyl)-benzoylamino]-8-methyl-2-oxo-2H-chromen-7-yloxy}-3-methoxy-2,2-dimethyl-tetrahydro-pyran-4-yl ester::Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-3-(3-methyl-but-2-enyl)-benzoylamino]-8-methyl-2-oxo-2H-chromen-7-yloxy}-3-methoxy-2,2-dimethyl-tetrahydro-pyran-4-yl ester(Novobiocin)::NOVOBIOCIN

SMILES: [#6]-[#8]-[#6@@H]1-[#6@@H](-[#8]-[#6](-[#7])=O)-[#6@@H](-[#8])-[#6@H](-[#8]-c2ccc3c(-[#8])c(-[#7]-[#6](=O)-c4ccc(-[#8])c(-[#6]\[#6]=[#6](/[#6])-[#6])c4)c(=O)oc3c2-[#6])-[#8]C1([#6])[#6]

InChI Key: InChIKey=BKRYLNPFZBMBFV-UHFFFAOYSA-N

Data: 4 KI  62 IC50  4 Kd  5 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 80 hits for monomerid = 50226181   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Heat shock protein HSP 90 (Rabbit)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Heat shock protein HSP 90-beta (Human)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.90E+5	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA polymerase theta (Human)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA polymerase theta (Human)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.44E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA polymerase theta (Human)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA polymerase theta (Human)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA polymerase theta (Human)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.650	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.68E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Microtubule-associated proteins 1A/1B light chain 3B (Human)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.74E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase A/A/B/B tetramer (Escherichia coli (strain K12))	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	408	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha/2-beta (Human)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>6.52E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase A/A/B/B tetramer (Escherichia coli (strain K12))	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	408	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit B (Mycobacterium smegmatis)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit B (Escherichia coli (strain K12))	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit B (Mycobacterium smegmatis)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit B (Escherichia coli (strain K12))	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit B (Staphylococcus aureus)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Microtubule-associated proteins 1A/1B light chain 3B (Human)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.72E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit B (Mycobacterium smegmatis)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit B (Mycobacterium smegmatis)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 4 subunit A/B (Staphylococcus aureus-Staphylococcus aureus (strai...)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase A/A/B/B tetramer (Escherichia coli (strain K12))	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 4 subunit A/B (Staphylococcus aureus-Staphylococcus aureus (strai...)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase A/A/B/B tetramer (Escherichia coli (strain K12))	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase A/A/B/B tetramer (Escherichia coli (strain K12))	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	408	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Nonstructural protein 3 (ZIKV)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.44E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit B (Staphylococcus aureus)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	125	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	408	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50226181 (Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	457	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair