BindingDB logo
myBDB logout

BDBM50226421 CHEMBL281589

SMILES: CCCCc1nc(Cl)c(CC(=O)OC)n1Cc1ccc(NC(=O)c2c(C)cccc2C(O)=O)cc1

InChI Key: InChIKey=LKRRFASIUJMGTQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50226421   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin II receptor


(RAT)
BDBM50226421
PNG
(CHEMBL281589)
Show SMILES CCCCc1nc(Cl)c(CC(=O)OC)n1Cc1ccc(NC(=O)c2c(C)cccc2C(O)=O)cc1
Show InChI InChI=1S/C26H28ClN3O5/c1-4-5-9-21-29-24(27)20(14-22(31)35-3)30(21)15-17-10-12-18(13-11-17)28-25(32)23-16(2)7-6-8-19(23)26(33)34/h6-8,10-13H,4-5,9,14-15H2,1-3H3,(H,28,32)(H,33,34)
PDB

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 32n/an/an/an/an/an/a



E. I. du Pont de Nemours & Company, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration that gave 50 percent displacement of specific binding of [3H]AII (2 nM) to Angiotensin II receptor


J Med Chem 33: 1312-29 (1990)


Article DOI: 10.1021/jm00167a007
BindingDB Entry DOI: 10.7270/Q2TM7DCT
More data for this
Ligand-Target Pair