BDBM50226465 CHEMBL402063::E-guggulsterone::pregna-4,17(20)-cis-diene-3,16-dione

SMILES: CC=C1C(=O)C[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C

InChI Key: InChIKey=WDXRGPWQVHZTQJ-UHFFFAOYSA-N

Data: 5 KI  9 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50226465   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bile acid receptor (Human)	BDBM50226465 (E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Mineralocorticoid receptor (Human)	BDBM50226465 (E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Human)	BDBM50226465 (E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
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Progesterone receptor (Human)	BDBM50226465 (E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Glucocorticoid receptor (Human)	BDBM50226465 (E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Bile acid receptor (Human)	BDBM50226465 (E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM50226465 (E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Bile acid receptor (Human)	BDBM50226465 (E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM50226465 (E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mineralocorticoid receptor (Human)	BDBM50226465 (E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...) Show SMILES Show InChI	GoogleScholar	UniChem		39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Progesterone receptor (Human)	BDBM50226465 (E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...) Show SMILES Show InChI	GoogleScholar	UniChem		201	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Glucocorticoid receptor (Human)	BDBM50226465 (E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...) Show SMILES Show InChI	GoogleScholar	UniChem		224	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Androgen receptor (Human)	BDBM50226465 (E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...) Show SMILES Show InChI	GoogleScholar	UniChem		240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Bile acid receptor (Human)	BDBM50226465 (E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...) Show SMILES Show InChI	GoogleScholar	UniChem		>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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