BindingDB logo
myBDB logout

BDBM50226785 CHEMBL174175

SMILES: CCCc1c(COc2cccc(Cc3nnn[nH]3)c2)ccc(C(C)=O)c1O

InChI Key: InChIKey=YNRLZKIONIAXNM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50226785   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cysteinyl leukotriene receptor


(Homo sapiens (Human))
BDBM50226785
PNG
(CHEMBL174175)
Show SMILES CCCc1c(COc2cccc(Cc3nnn[nH]3)c2)ccc(C(C)=O)c1O
Show InChI InChI=1S/C20H22N4O3/c1-3-5-18-15(8-9-17(13(2)25)20(18)26)12-27-16-7-4-6-14(10-16)11-19-21-23-24-22-19/h4,6-10,26H,3,5,11-12H2,1-2H3,(H,21,22,23,24)
PDB

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 100n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of LTD4-induced contraction in guinea pig ileum


J Med Chem 30: 911-8 (1987)


Article DOI: 10.1021/jm00388a028
BindingDB Entry DOI: 10.7270/Q25X2B45
More data for this
Ligand-Target Pair