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BDBM50226875 CHEMBL27416

SMILES: Cc1cn(cn1)-c1ccc(cc1)C(=O)c1[nH]c(O)nc1C

InChI Key: InChIKey=LLYKFIBMPZWPML-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50226875   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 4


(Homo sapiens (Human))
BDBM50226875
PNG
(CHEMBL27416)
Show SMILES Cc1cn(cn1)-c1ccc(cc1)C(=O)c1[nH]c(O)nc1C
Show InChI InChI=1S/C15H14N4O2/c1-9-7-19(8-16-9)12-5-3-11(4-6-12)14(20)13-10(2)17-15(21)18-13/h3-8H,1-2H3,(H2,17,18,21)
PDB

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.50E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of canine cardiac cAMP phosphodiesterase (cAMP-PDE)


J Med Chem 30: 1342-7 (1987)


Article DOI: 10.1021/jm00391a013
BindingDB Entry DOI: 10.7270/Q2DV1N40
More data for this
Ligand-Target Pair