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BDBM50226883 CHEMBL282138

SMILES: CCc1[nH]c(O)nc1C(=O)c1ccc(cc1)-n1ccnc1C(C)C

InChI Key: InChIKey=AKYFKJZJHKXCSJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50226883   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 4


(Homo sapiens (Human))
BDBM50226883
PNG
(CHEMBL282138)
Show SMILES CCc1[nH]c(O)nc1C(=O)c1ccc(cc1)-n1ccnc1C(C)C
Show InChI InChI=1S/C18H20N4O2/c1-4-14-15(21-18(24)20-14)16(23)12-5-7-13(8-6-12)22-10-9-19-17(22)11(2)3/h5-11H,4H2,1-3H3,(H2,20,21,24)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of canine cardiac cAMP phosphodiesterase (cAMP-PDE)


J Med Chem 30: 1342-7 (1987)


Article DOI: 10.1021/jm00391a013
BindingDB Entry DOI: 10.7270/Q2DV1N40
More data for this
Ligand-Target Pair