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BDBM50227100 2-(1-(4-chloro-3-ethoxybenzyl)piperidin-4-ylamino)benzo[d]oxazole-5-sulfonamide::CHEMBL391637

SMILES: CCOc1cc(CN2CCC(CC2)Nc2nc3cc(ccc3o2)S(N)(=O)=O)ccc1Cl

InChI Key: InChIKey=FRXWQHQATAUDCR-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50227100   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM50227100
PNG
(2-(1-(4-chloro-3-ethoxybenzyl)piperidin-4-ylamino)...)
Show SMILES CCOc1cc(CN2CCC(CC2)Nc2nc3cc(ccc3o2)S(N)(=O)=O)ccc1Cl
Show InChI InChI=1S/C21H25ClN4O4S/c1-2-29-20-11-14(3-5-17(20)22)13-26-9-7-15(8-10-26)24-21-25-18-12-16(31(23,27)28)4-6-19(18)30-21/h3-6,11-12,15H,2,7-10,13H2,1H3,(H,24,25)(H2,23,27,28)
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PC cid
PC sid
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Similars

Article
PubMed
17n/an/an/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd.

Curated by ChEMBL


Assay Description
Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells


J Med Chem 50: 6291-4 (2007)


Article DOI: 10.1021/jm701143p
BindingDB Entry DOI: 10.7270/Q2WS8T0K
More data for this
Ligand-Target Pair