BDBM50227107 2-(1-(3-ethoxy-4-methoxybenzyl)piperidin-4-ylamino)benzo[d]oxazole-5-sulfonamide::CHEMBL393718

SMILES CCOc1cc(CN2CCC(CC2)Nc2nc3cc(ccc3o2)S(N)(=O)=O)ccc1OC

InChI Key InChIKey=SYNXMLXHBZIEOT-UHFFFAOYSA-N

Data  6 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50227107   

TargetSomatostatin receptor type 5(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227107(2-(1-(3-ethoxy-4-methoxybenzyl)piperidin-4-ylamino...)
Affinity DataKi:  185nMAssay Description:Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227107(2-(1-(3-ethoxy-4-methoxybenzyl)piperidin-4-ylamino...)
Affinity DataKi:  520nMAssay Description:Binding affinity to human histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227107(2-(1-(3-ethoxy-4-methoxybenzyl)piperidin-4-ylamino...)
Affinity DataKi:  529nMAssay Description:Displacement of SST14 from human recombinant SST5 receptor expressed in CHO cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227107(2-(1-(3-ethoxy-4-methoxybenzyl)piperidin-4-ylamino...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of SST14 from human recombinant SST2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227107(2-(1-(3-ethoxy-4-methoxybenzyl)piperidin-4-ylamino...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of SST14 from human recombinant SST3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227107(2-(1-(3-ethoxy-4-methoxybenzyl)piperidin-4-ylamino...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of SST14 from human recombinant SST4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227107(2-(1-(3-ethoxy-4-methoxybenzyl)piperidin-4-ylamino...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of hERG channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227107(2-(1-(3-ethoxy-4-methoxybenzyl)piperidin-4-ylamino...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed