BDBM50227145 2-(5-((3-(3-methyl-8-(trifluoromethyl)quinolin-4-yl)phenyl)methylamino)naphthalen-1-yl)acetic acid::CHEMBL442437

SMILES Cc1cnc2c(cccc2c1-c1cccc(CNc2cccc3c(CC(O)=O)cccc23)c1)C(F)(F)F

InChI Key InChIKey=OHDRXCKGYPYQAU-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50227145   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50227145(2-(5-((3-(3-methyl-8-(trifluoromethyl)quinolin-4-y...)
Affinity DataEC50:  4.17E+3nMAssay Description:Agonist activity at human LXRbeta expressed in Huh7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50227145(2-(5-((3-(3-methyl-8-(trifluoromethyl)quinolin-4-y...)
Affinity DataIC50:  10nMAssay Description:Binding affinity at human LXRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50227145(2-(5-((3-(3-methyl-8-(trifluoromethyl)quinolin-4-y...)
Affinity DataEC50:  7.87E+3nMAssay Description:Agonist activity at human LXRalpha expressed in Huh7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50227145(2-(5-((3-(3-methyl-8-(trifluoromethyl)quinolin-4-y...)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human recombinant PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50227145(2-(5-((3-(3-methyl-8-(trifluoromethyl)quinolin-4-y...)
Affinity DataIC50:  211nMAssay Description:Binding affinity at human LXRalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed