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BDBM50227904 CHEMBL74961

SMILES: Cc1c(Cl)cccc1NC(=O)N(Cc1ccccc1)Cc1ccccc1

InChI Key: InChIKey=ZCXXQJWBFZKNCZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50227904   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50227904
PNG
(CHEMBL74961)
Show SMILES Cc1c(Cl)cccc1NC(=O)N(Cc1ccccc1)Cc1ccccc1
Show InChI InChI=1S/C22H21ClN2O/c1-17-20(23)13-8-14-21(17)24-22(26)25(15-18-9-4-2-5-10-18)16-19-11-6-3-7-12-19/h2-14H,15-16H2,1H3,(H,24,26)
PDB

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Article
PubMed
n/an/a 8.49E+3n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Acyl coenzyme A:cholesterol acyltransferase derived from rat adrenals


J Med Chem 32: 2318-25 (1989)


Article DOI: 10.1021/jm00130a016
BindingDB Entry DOI: 10.7270/Q2QZ2D5R
More data for this
Ligand-Target Pair