BDBM50227988 (6S,7S)-6-[4-(3,5-dichloro-phenyl)-3,6-dihydro-2H-pyridine-1-carbonyl]-5-aza-spiro[2.5]octane-7-carboxylic acid hydroxyamide::CHEMBL403022

SMILES ONC(=O)[C@H]1CC2(CC2)CN[C@@H]1C(=O)N1CCC(=CC1)c1cc(Cl)cc(Cl)c1

InChI Key InChIKey=IKZZUHATDHDZKR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50227988   

LigandPNGBDBM50227988((6S,7S)-6-[4-(3,5-dichloro-phenyl)-3,6-dihydro-2H-...)
Affinity DataIC50: 99nMAssay Description:Inhibition of HER2 sheddase in BT474 cells by extracellular domain shedding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50227988((6S,7S)-6-[4-(3,5-dichloro-phenyl)-3,6-dihydro-2H-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Binding affinity to MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed