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BDBM50228206 DEXETIMIDE::Dexetimide::R-16470 [as hydrochloride]

SMILES: O=C1CC[C@@](C2CCN(Cc3ccccc3)CC2)(C(=O)N1)c1ccccc1

InChI Key: InChIKey=LQQIVYSCPWCSSD-HSZRJFAPSA-N

Data: 1 IC50

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Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50228206   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor


(Mus musculus)
BDBM50228206
PNG
(DEXETIMIDE | Dexetimide | R-16470 [as hydrochlorid...)
Show SMILES O=C1CC[C@@](C2CCN(Cc3ccccc3)CC2)(C(=O)N1)c1ccccc1
Show InChI InChI=1S/C23H26N2O2/c26-21-11-14-23(22(27)24-21,19-9-5-2-6-10-19)20-12-15-25(16-13-20)17-18-7-3-1-4-8-18/h1-10,20H,11-17H2,(H,24,26,27)/t23-/m1/s1
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PC cid
PC sid
UniChem

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Similars

Article
PubMed
n/an/a 3.30n/an/an/an/an/an/a



Johns Hopkins Medical Institutions

Curated by ChEMBL


Assay Description
Ability (10 ug/kg) to inhibit binding of [125I]iododexetimide to muscarinic receptor in mice


J Med Chem 32: 1057-62 (1989)


Article DOI: 10.1021/jm00125a021
BindingDB Entry DOI: 10.7270/Q29S1T87
More data for this
Ligand-Target Pair