BDBM50228238 CHEMBL30911

SMILES CO\C(O)=C1\C(C(C(=O)OCCN(C)CC2COc3ccccc3O2)=C(C)N=C1C)c1ccccc1[N+]([O-])=O

InChI Key InChIKey=YPULZJXQBKVULX-SOYKGTTHSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50228238   

TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228238(CHEMBL30911)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro ability to inhibit norepinephrine binding to alpha-2 adrenergic receptor of guinea pig vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228238(CHEMBL30911)
Affinity DataIC50: >1.00E+4nMAssay Description:Alpha-1-adrenolytic activity was assessed in vitro from the ability to inhibit clonidine binding to rat aorta preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50228238(CHEMBL30911)
Affinity DataIC50:  270nMAssay Description:Ability to inhibit [3H]yohimbine binding to alpha-2 adrenergic receptor of rat cerebral cortex preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228238(CHEMBL30911)
Affinity DataIC50:  300nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed