BDBM50228363 CHEMBL257991::N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)quinoxaline-2-carboxamide::SRT-1720

SMILES: O=C(Nc1ccccc1-c1cn2c(CN3CCNCC3)csc2n1)c1cnc2ccccc2n1

InChI Key: InChIKey=IASPBORHOMBZMY-UHFFFAOYSA-N

Data: 6 IC50  6 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50228363   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent protein deacetylase sirtuin-3, mitochondrial (Human)	BDBM50228363 (N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
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NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50228363 (N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50228363 (N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor (Human)	BDBM50228363 (N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M1 (Human)	BDBM50228363 (N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M2 (Human)	BDBM50228363 (N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent noradrenaline transporter (Human)	BDBM50228363 (N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
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NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50228363 (N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50228363 (N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a
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NAD-dependent protein deacetylase sirtuin-3, mitochondrial (Human)	BDBM50228363 (N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50228363 (N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50228363 (N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair