BDBM50228364 3,4,5-trimethoxy-N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)benzamide::CHEMBL254156::SRT-1460

SMILES: COc1cc(cc(OC)c1OC)C(=O)Nc1ccccc1-c1cn2c(CN3CCNCC3)csc2n1

InChI Key: InChIKey=SBEWVVLMFLTQFE-UHFFFAOYSA-N

Data: 2 Kd  4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50228364   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50228364 (3,4,5-trimethoxy-N-(2-(3-(piperazin-1-ylmethyl)imi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.62E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50228364 (3,4,5-trimethoxy-N-(2-(3-(piperazin-1-ylmethyl)imi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.62E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50228364 (3,4,5-trimethoxy-N-(2-(3-(piperazin-1-ylmethyl)imi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50228364 (3,4,5-trimethoxy-N-(2-(3-(piperazin-1-ylmethyl)imi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-3, mitochondrial (Human)	BDBM50228364 (3,4,5-trimethoxy-N-(2-(3-(piperazin-1-ylmethyl)imi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50228364 (3,4,5-trimethoxy-N-(2-(3-(piperazin-1-ylmethyl)imi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair