BindingDB logo
myBDB logout

BDBM50228817 CHEMBL83350

SMILES: O=c1ccoc2cc(OCCCN3CCCN(CC3)c3ccccc3)ccc12

InChI Key: InChIKey=VFBLFLJKKDSTDZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50228817   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50228817
PNG
(CHEMBL83350)
Show SMILES O=c1ccoc2cc(OCCCN3CCCN(CC3)c3ccccc3)ccc12
Show InChI InChI=1S/C23H26N2O3/c26-22-10-17-28-23-18-20(8-9-21(22)23)27-16-5-12-24-11-4-13-25(15-14-24)19-6-2-1-3-7-19/h1-3,6-10,17-18H,4-5,11-16H2
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 884n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Compound was tested for inhibitory binding activity against Dopamine receptor in rat striatal membranes using [3H]HAL as the radioligand.


J Med Chem 34: 248-56 (1991)


Article DOI: 10.1021/jm00105a039
BindingDB Entry DOI: 10.7270/Q20Z73WT
More data for this
Ligand-Target Pair