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BDBM50229250 CHEMBL304293

SMILES: CCO\C(O)=C1\C(c2ccco2)C(C#N)=C(C)N=C1CS(=O)(=O)c1ccccc1

InChI Key: InChIKey=RKONXIURGYGSAE-QZQOTICOSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50229250   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-dependent L-type calcium channel subunit alpha-1S


(Rattus norvegicus)
BDBM50229250
PNG
(CHEMBL304293)
Show SMILES CCO\C(O)=C1\C(c2ccco2)C(C#N)=C(C)N=C1CS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C21H20N2O5S/c1-3-27-21(24)20-17(13-29(25,26)15-8-5-4-6-9-15)23-14(2)16(12-22)19(20)18-10-7-11-28-18/h4-11,19,24H,3,13H2,1-2H3/b21-20+
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 254n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Affinity to bind dihydropyridine receptor (DHP receptor) by inhibiting the radioligand [3H]nitrendipine


J Med Chem 34: 2248-60 (1991)


Article DOI: 10.1021/jm00111a047
More data for this
Ligand-Target Pair