BindingDB logo
myBDB logout

BDBM50229264 CHEMBL72305

SMILES: CCO\C(O)=C1\C(C(C#N)=C(C)N=C1CSc1ccccc1F)c1ccccc1C(F)(F)F

InChI Key: InChIKey=PVTRVVKCASWVSD-GHVJWSGMSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50229264   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-dependent L-type calcium channel subunit alpha-1S


(Rattus norvegicus)
BDBM50229264
PNG
(CHEMBL72305)
Show SMILES CCO\C(O)=C1\C(C(C#N)=C(C)N=C1CSc1ccccc1F)c1ccccc1C(F)(F)F
Show InChI InChI=1S/C24H20F4N2O2S/c1-3-32-23(31)22-19(13-33-20-11-7-6-10-18(20)25)30-14(2)16(12-29)21(22)15-8-4-5-9-17(15)24(26,27)28/h4-11,21,31H,3,13H2,1-2H3/b23-22+
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 267n/an/an/an/an/an/a


TBA

Assay Description
Affinity to bind dihydropyridine receptor (DHP receptor) by inhibiting the radioligand [3H]nitrendipine


Citation and Details

Article DOI: 10.1021/jm00111a047
More data for this
Ligand-Target Pair