BDBM50229731 CHEMBL4080823

SMILES C1CCN(CC1)c1nc(Nc2ccc(cc2)-c2ccno2)nc(n1)N1CCCCC1

InChI Key InChIKey=HBMHAKLSXFYMKT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50229731   

TargetProstaglandin G/H synthase 2(Human)
Beni-Suef University

Curated by ChEMBL
LigandPNGBDBM50229731(CHEMBL4080823)
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of human COX2 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by enzyme i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Beni-Suef University

Curated by ChEMBL
LigandPNGBDBM50229731(CHEMBL4080823)
Affinity DataIC50: 7.23E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by enzyme i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed