BDBM50230813 (3R,6S,9S,12S,25aS)-6-(3-carbamimidamidopropyl)-9-(1H-indol-3-ylmethyl)-3-(naphthalen-2-ylmethyl)-1,4,7,10,18,21-hexaoxo-1H,2H,3H,4H,5H,6H,7H,8H,9H,10H,11H,12H,13H,14H,15H,16H,17H,18H,21H,23H,24H,25H,25aH-pyrrolo[2,1-l]1,4,7,10,13,18-hexaazacyclotricosane-12-carboxamide::CHEMBL398635
SMILES NC(=N)NCCC[C@@H]1NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@@H]2CCCN2C(=O)C=CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O)C(N)=O
InChI Key InChIKey=YTZPUJBWCYPFRS-GJOOVXBSSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50230813
Affinity DataIC50: 20nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alpha-MSH from human MC3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 520nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alpha-MSH from human MC4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Agonist activity at human MC1 receptor expressed in HEK293 cells assessed as intracellular cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Agonist activity at human MC5 receptor expressed in HEK293 cells assessed as intracellular cAMP accumulationMore data for this Ligand-Target Pair