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BDBM50230987 CHEMBL4071293

SMILES: C\N=C(/N(C)C)N(C)c1nc(Nc2ccccc2)nc(n1)N1C(CC(C)C)C(=O)N=C1N

InChI Key: InChIKey=GJVCTWZJWRVIME-XTQSDGFTSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50230987   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Atrial natriuretic peptide receptor


(Homo sapiens)
BDBM50230987
PNG
(CHEMBL4071293)
Show SMILES C\N=C(/N(C)C)N(C)c1nc(Nc2ccccc2)nc(n1)N1C(CC(C)C)C(=O)N=C1N
Show InChI InChI=1S/C21H30N10O/c1-13(2)12-15-16(32)25-17(22)31(15)20-27-18(24-14-10-8-7-9-11-14)26-19(28-20)30(6)21(23-3)29(4)5/h7-11,13,15H,12H2,1-6H3,(H2,22,25,32)(H,24,26,27,28)/b23-21+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
PubMed
n/an/an/an/a 6.40E+4n/an/an/an/a



Asubio Pharma Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human NPR-A expressed in CHO cells assessed as increase in cGMP accumulation after 30 mins by radioimmunoassay


Bioorg Med Chem 25: 1762-1769 (2017)

More data for this
Ligand-Target Pair