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BDBM50231109 CHEMBL254899::N-(2,6-dichlorophenethyl)-4-(trifluoromethoxy)benzamide

SMILES: FC(F)(F)Oc1ccc(cc1)C(=O)NCCc1c(Cl)cccc1Cl

InChI Key: InChIKey=DTYPHLFPAYZOQQ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50231109   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM50231109
PNG
(CHEMBL254899 | N-(2,6-dichlorophenethyl)-4-(triflu...)
Show SMILES FC(F)(F)Oc1ccc(cc1)C(=O)NCCc1c(Cl)cccc1Cl
Show InChI InChI=1S/C16H12Cl2F3NO2/c17-13-2-1-3-14(18)12(13)8-9-22-15(23)10-4-6-11(7-5-10)24-16(19,20)21/h1-7H,8-9H2,(H,22,23)
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 205n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced calcium influx in HEK293 cells


Bioorg Med Chem Lett 18: 1072-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.007
BindingDB Entry DOI: 10.7270/Q2PZ58K9
More data for this
Ligand-Target Pair