BDBM50231393 CHEMBL4073167

SMILES [O-][N+](=O)c1cc(ccc1Cl)S(=O)(=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cn(Cc2ccc(cc2)-c2ccc(Cl)cc2)c2ccccc12

InChI Key InChIKey=AZRHKOKLZALSIL-XIFFEERXSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50231393   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50231393(CHEMBL4073167)
Affinity DataKi:  72nMAssay Description:Inhibition of N-terminal FAM-labeled Bid-BH3 peptide binding to MCL1 (unknown origin) preincubated for 30 mins followed by N-terminal FAM-labeled Bid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50231393(CHEMBL4073167)
Affinity DataKi:  260nMAssay Description:Inhibition of N-terminal FAM-labeled Bid-BH3 peptide binding to Bcl2 (unknown origin) preincubated for 30 mins followed by N-terminal FAM-labeled Bid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50231393(CHEMBL4073167)
Affinity DataKi:  710nMAssay Description:Inhibition of N-terminal FAM-labeled Bid-BH3 peptide binding to Bcl-XL (unknown origin) preincubated for 30 mins followed by N-terminal FAM-labeled B...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed