BDBM16751 (N-(diaminomethylene)-2,4-diphenyl-1H-pyrrole-1-acetamide)::Acylguanidine, 7a::CHEMBL217068::N-(diaminomethylidene)-2-(2,5-diphenyl-1H-pyrrol-1-yl)acetamide

SMILES: NC(=N)NC(=O)Cn1c(ccc1-c1ccccc1)-c1ccccc1

InChI Key: InChIKey=WVLDNAVUCUAGDP-UHFFFAOYSA-N

Data: 10 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 16751   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Human)	BDBM16751 ((N-(diaminomethylene)-2,4-diphenyl-1H-pyrrole-1-ac...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	4.5	22
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Beta-secretase 2 (Human)	BDBM16751 ((N-(diaminomethylene)-2,4-diphenyl-1H-pyrrole-1-ac...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	4.5	22
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Cathepsin D (Human)	BDBM16751 ((N-(diaminomethylene)-2,4-diphenyl-1H-pyrrole-1-ac...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	4.5	22
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Pepsin A-4 (Human)	BDBM16751 ((N-(diaminomethylene)-2,4-diphenyl-1H-pyrrole-1-ac...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	4.5	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-secretase 1 (Human)	BDBM16751 ((N-(diaminomethylene)-2,4-diphenyl-1H-pyrrole-1-ac...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-secretase 1 (Human)	BDBM16751 ((N-(diaminomethylene)-2,4-diphenyl-1H-pyrrole-1-ac...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-secretase 2 (Human)	BDBM16751 ((N-(diaminomethylene)-2,4-diphenyl-1H-pyrrole-1-ac...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cathepsin D (Human)	BDBM16751 ((N-(diaminomethylene)-2,4-diphenyl-1H-pyrrole-1-ac...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-secretase 1 (Human)	BDBM16751 ((N-(diaminomethylene)-2,4-diphenyl-1H-pyrrole-1-ac...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-secretase 1 (Human)	BDBM16751 ((N-(diaminomethylene)-2,4-diphenyl-1H-pyrrole-1-ac...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair