BDBM50231681 3-(ethylamino)-N-((2S,3R)-3-hydroxy-1-phenyl-4-(phenylamino)butan-2-yl)-5-(2-oxopyrrolidin-1-yl)benzamide::CHEMBL252861

SMILES CCNc1cc(cc(c1)C(=O)N[C@@H](Cc1ccccc1)[C@H](O)CNc1ccccc1)N1CCCC1=O

InChI Key InChIKey=SFMOCUPWKLWIBH-RRPNLBNLSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50231681   

TargetBeta-secretase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50231681(3-(ethylamino)-N-((2S,3R)-3-hydroxy-1-phenyl-4-(ph...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50231681(3-(ethylamino)-N-((2S,3R)-3-hydroxy-1-phenyl-4-(ph...)
Affinity DataIC50:  2.14E+4nMAssay Description:Inhibition of BACE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50231681(3-(ethylamino)-N-((2S,3R)-3-hydroxy-1-phenyl-4-(ph...)
Affinity DataIC50:  4.68E+3nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed