BDBM50232654 CHEMBL403695::N-(2-aminophenyl)-4-((6-(pyridin-3-ylmethylamino)benzo[d]thiazol-2-ylthio)methyl)benzamide

SMILES Nc1ccccc1NC(=O)c1ccc(CSc2nc3ccc(NCc4cccnc4)cc3s2)cc1

InChI Key InChIKey=AAXGKCJKCNFLDR-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50232654   

TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232654(CHEMBL403695 | N-(2-aminophenyl)-4-((6-(pyridin-3-...)
Affinity DataEC50:  2.00E+3nMAssay Description:Inhibition of HDAC1 in human T24 cells assessed as induction of histone H4 acetylation after 16 hrs relative to MS-275More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232654(CHEMBL403695 | N-(2-aminophenyl)-4-((6-(pyridin-3-...)
Affinity DataIC50:  800nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed