BDBM50233222 CHEMBL4082248

SMILES CCCCCCCCCC[C@@H]1NC(=N)N[C@]2(CCCO2)[C@@H]1C(O)=O

InChI Key InChIKey=XQIBJGYYXKVIHB-MPGHIAIKSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50233222   

TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Tohoku University

Curated by ChEMBL
LigandPNGBDBM50233222(CHEMBL4082248)
Affinity DataIC50:  7.5nMAssay Description:Antagonist activity at human Nav1.2 expressed in HEK293T cells assessed as inhibition of VTD-induced sustained current by whole cell patch clamp meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Tohoku University

Curated by ChEMBL
LigandPNGBDBM50233222(CHEMBL4082248)
Affinity DataEC50:  79nMAssay Description:Inhibition of Nav1.2 (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Tohoku University

Curated by ChEMBL
LigandPNGBDBM50233222(CHEMBL4082248)
Affinity DataIC50:  35nMAssay Description:Antagonist activity at human Nav1.2 expressed in HEK293T cells assessed as inhibition of VTD-induced tail current by whole cell patch clamp method re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed