BDBM50233225 CHEMBL4071864::US12065447, Compound GSK2982772

SMILES: CN1c2ccccc2OC[C@H](NC(=O)c2n[nH]c(Cc3ccccc3)n2)C1=O

InChI Key: InChIKey=LYPAFUINURXJSG-UHFFFAOYSA-N

Data: 2 KI  16 IC50  2 Kd  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 50233225   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-interacting serine/threonine-protein kinase 1 (Human)	BDBM50233225 (CHEMBL4071864 | US12065447, Compound GSK2982772 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Receptor-interacting serine/threonine-protein kinase 1 (Human)	BDBM50233225 (CHEMBL4071864 | US12065447, Compound GSK2982772 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Human)	BDBM50233225 (CHEMBL4071864 | US12065447, Compound GSK2982772 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Human)	BDBM50233225 (CHEMBL4071864 | US12065447, Compound GSK2982772 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Human)	BDBM50233225 (CHEMBL4071864 | US12065447, Compound GSK2982772 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM50233225 (CHEMBL4071864 | US12065447, Compound GSK2982772 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50233225 (CHEMBL4071864 | US12065447, Compound GSK2982772 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.95E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50233225 (CHEMBL4071864 | US12065447, Compound GSK2982772 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor-interacting serine/threonine-protein kinase 1 (Mouse)	BDBM50233225 (CHEMBL4071864 | US12065447, Compound GSK2982772 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Mouse)	BDBM50233225 (CHEMBL4071864 | US12065447, Compound GSK2982772 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Human)	BDBM50233225 (CHEMBL4071864 | US12065447, Compound GSK2982772 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Human)	BDBM50233225 (CHEMBL4071864 | US12065447, Compound GSK2982772 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Human)	BDBM50233225 (CHEMBL4071864 | US12065447, Compound GSK2982772 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Human)	BDBM50233225 (CHEMBL4071864 | US12065447, Compound GSK2982772 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Receptor-interacting serine/threonine-protein kinase 3 (Human)	BDBM50233225 (CHEMBL4071864 | US12065447, Compound GSK2982772 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Human)	BDBM50233225 (CHEMBL4071864 | US12065447, Compound GSK2982772 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Human)	BDBM50233225 (CHEMBL4071864 | US12065447, Compound GSK2982772 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Human)	BDBM50233225 (CHEMBL4071864 | US12065447, Compound GSK2982772 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Human)	BDBM50233225 (CHEMBL4071864 | US12065447, Compound GSK2982772 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Human)	BDBM50233225 (CHEMBL4071864 | US12065447, Compound GSK2982772 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Human)	BDBM50233225 (CHEMBL4071864 | US12065447, Compound GSK2982772 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Human)	BDBM50233225 (CHEMBL4071864 | US12065447, Compound GSK2982772 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Human)	BDBM50233225 (CHEMBL4071864 | US12065447, Compound GSK2982772 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Human)	BDBM50233225 (CHEMBL4071864 | US12065447, Compound GSK2982772 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		0.977	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Human)	BDBM50233225 (CHEMBL4071864 | US12065447, Compound GSK2982772 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair