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BDBM50234410 (4-chloro-3-(pyrrolidin-1-ylsulfonyl)phenyl)((trans)-octahydroisoquinolin-2(1H)-yl)methanone::CHEMBL252044

SMILES: Clc1ccc(cc1S(=O)(=O)N1CCCC1)C(=O)N1CC[C@@H]2CCCC[C@H]2C1

InChI Key: InChIKey=DIZIUMQHNNQQSK-RDJZCZTQSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50234410   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50234410
PNG
((4-chloro-3-(pyrrolidin-1-ylsulfonyl)phenyl)((tran...)
Show SMILES Clc1ccc(cc1S(=O)(=O)N1CCCC1)C(=O)N1CC[C@@H]2CCCC[C@H]2C1
Show InChI InChI=1S/C20H27ClN2O3S/c21-18-8-7-16(13-19(18)27(25,26)23-10-3-4-11-23)20(24)22-12-9-15-5-1-2-6-17(15)14-22/h7-8,13,15,17H,1-6,9-12,14H2/t15-,17-/m0/s1
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Similars

Article
PubMed
n/an/an/an/a 3n/an/an/an/a



Evotec (UK) Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level


Bioorg Med Chem Lett 18: 1725-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.042
BindingDB Entry DOI: 10.7270/Q2X92B1F
More data for this
Ligand-Target Pair