BDBM50235385 APD-811::Ralinepag

SMILES: OC(=O)COC[C@H]1CC[C@H](COC(=O)N(c2ccccc2)c2ccc(Cl)cc2)CC1

InChI Key: InChIKey=NPDKXVKJRHPDQT-UHFFFAOYSA-N

Data: 7 KI  8 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50235385   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostacyclin receptor (Human)	BDBM50235385 (APD-811 | Ralinepag) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50235385 (APD-811 | Ralinepag) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50235385 (APD-811 | Ralinepag) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50235385 (APD-811 | Ralinepag) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C8 (Human)	BDBM50235385 (APD-811 | Ralinepag) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50235385 (APD-811 | Ralinepag) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50235385 (APD-811 | Ralinepag) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin D2 receptor (Human)	BDBM50235385 (APD-811 | Ralinepag) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	850	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50235385 (APD-811 | Ralinepag) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Prostacyclin receptor (Human)	BDBM50235385 (APD-811 | Ralinepag) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8.5	n/a	n/a	n/a	n/a
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Prostacyclin receptor (Rat)	BDBM50235385 (APD-811 | Ralinepag) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	530	n/a	n/a	n/a	n/a
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Prostacyclin receptor (Human)	BDBM50235385 (APD-811 | Ralinepag) Show SMILES Show InChI	GoogleScholar	UniChem		3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Prostacyclin receptor (Rat)	BDBM50235385 (APD-811 | Ralinepag) Show SMILES Show InChI	GoogleScholar	UniChem		76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin E2 receptor EP3 subtype (Human)	BDBM50235385 (APD-811 | Ralinepag) Show SMILES Show InChI	GoogleScholar	UniChem		143	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin E2 receptor EP2 subtype (Human)	BDBM50235385 (APD-811 | Ralinepag) Show SMILES Show InChI	GoogleScholar	UniChem		610	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin E2 receptor EP4 subtype (Human)	BDBM50235385 (APD-811 | Ralinepag) Show SMILES Show InChI	GoogleScholar	UniChem		678	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin D2 receptor (Human)	BDBM50235385 (APD-811 | Ralinepag) Show SMILES Show InChI	GoogleScholar	UniChem		2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin E2 receptor EP1 subtype (Human)	BDBM50235385 (APD-811 | Ralinepag) Show SMILES Show InChI	GoogleScholar	UniChem		9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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