BDBM50235763 (2R,3R)-methyl 2-(1-(2-((S)-1-amino-2-methylpropyl)-4-methylphenyl)piperazine-4-carbonyl)-3-(4-chlorophenyl)pyrrolidine-1-carboxylate::CHEMBL255100

SMILES COC(=O)N1CC[C@@H]([C@@H]1C(=O)N1CCN(CC1)c1ccc(C)cc1[C@@H](N)C(C)C)c1ccc(Cl)cc1

InChI Key InChIKey=QFNYNYUWRSANTP-ZSQFBXSQSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50235763   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50235763((2R,3R)-methyl 2-(1-(2-((S)-1-amino-2-methylpropyl...)
Affinity DataKi:  17nMAssay Description:Displacement of [125]NDPMSH from human MC4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50235763((2R,3R)-methyl 2-(1-(2-((S)-1-amino-2-methylpropyl...)
Affinity DataKi:  18nMAssay Description:Displacement of [125]NDPMSH from human MC4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50235763((2R,3R)-methyl 2-(1-(2-((S)-1-amino-2-methylpropyl...)
Affinity DataIC50:  720nMAssay Description:Antagonist activity at MC4 receptor assessed as inhibition of alpha-MSH-stimulated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed