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BDBM50235849 (4-hydroxy-butyl)-carbamic acid 2-{5-[(S)-1-(2-amino-2-methyl-propionylamino)-2-(2-methyl-benzyloxy)-ethyl]-tetrazol-1-yl}-ethyl ester::CHEMBL404354

SMILES: Cc1ccccc1COC[C@@H](NC(=O)C(C)(C)N)c1nnnn1CCOC(=O)NCCCCO

InChI Key: InChIKey=AXABYTPCUMEGOG-GOSISDBHSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50235849   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ghrelin receptor


(Homo sapiens (Human))
BDBM50235849
PNG
((4-hydroxy-butyl)-carbamic acid 2-{5-[(S)-1-(2-ami...)
Show SMILES Cc1ccccc1COC[C@@H](NC(=O)C(C)(C)N)c1nnnn1CCOC(=O)NCCCCO
Show InChI InChI=1S/C22H35N7O5/c1-16-8-4-5-9-17(16)14-33-15-18(25-20(31)22(2,3)23)19-26-27-28-29(19)11-13-34-21(32)24-10-6-7-12-30/h4-5,8-9,18,30H,6-7,10-15,23H2,1-3H3,(H,24,32)(H,25,31)/t18-/m1/s1
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PC cid
PC sid
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Similars

Article
PubMed
n/an/an/an/a 0.510n/an/an/an/a



Princ

Curated by ChEMBL


Assay Description
Inhibition of human growth hormone secretagogue receptor assessed as measuring intracellular calcium level by FLIPR assay


Bioorg Med Chem Lett 18: 1825-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.021
BindingDB Entry DOI: 10.7270/Q24B325H
More data for this
Ligand-Target Pair