BDBM50236033 CHEMBL4087478

SMILES CCC(=O)Nc1cc(Nc2ncc(C(=O)Nc3cc(NC(=O)c4cc(OC)c(OC)c(OC)c4)ccc3C)c(NC)n2)ccc1C

InChI Key InChIKey=JJORFRRMKVGMOJ-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50236033   

TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50236033(CHEMBL4087478)
Affinity DataIC50:  230nMAssay Description:Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50236033(CHEMBL4087478)
Affinity DataEC50:  197nMAssay Description:Irreversible inhibition of inactive state of wild-type full-length recombinant His-tagged BMX phosphorylation (unknown origin) at tyrosine residue ex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50236033(CHEMBL4087478)
Affinity DataIC50:  89nMAssay Description:Inhibition of full-length recombinant human GST-tagged p38alpha expressed in Escherichia coli by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50236033(CHEMBL4087478)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was evaluated for 50% inhibition of PTP1B using uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50236033(CHEMBL4087478)
Affinity DataIC50:  212nMAssay Description:Inhibition of human GST-tagged DDR1 catalytic domain expressed in baculovirus expression system by LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed