BDBM50236033 CHEMBL4087478
SMILES CCC(=O)Nc1cc(Nc2ncc(C(=O)Nc3cc(NC(=O)c4cc(OC)c(OC)c(OC)c4)ccc3C)c(NC)n2)ccc1C
InChI Key InChIKey=JJORFRRMKVGMOJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50236033
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataEC50: 197nMAssay Description:Irreversible inhibition of inactive state of wild-type full-length recombinant His-tagged BMX phosphorylation (unknown origin) at tyrosine residue ex...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 89nMAssay Description:Inhibition of full-length recombinant human GST-tagged p38alpha expressed in Escherichia coli by Z'-LYTE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was evaluated for 50% inhibition of PTP1B using uM)More data for this Ligand-Target Pair
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 212nMAssay Description:Inhibition of human GST-tagged DDR1 catalytic domain expressed in baculovirus expression system by LanthaScreen assayMore data for this Ligand-Target Pair