BDBM50236230 2-((R)-4-((3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)ethanesulfonic acid::CHEMBL272427::ursodeoxy cholic acid
SMILES C[C@H](CCC(=O)NCCS(O)(=O)=O)[C@H]1CC[C@H]2[C@@H]3[C@@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
InChI Key InChIKey=BHTRKEVKTKCXOH-LBSADWJPSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50236230
TargetIleal sodium/bile acid cotransporter(Homo sapiens (Human))
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataKi: 2.80E+4nMAssay Description:TP_TRANSPORTER: inhibition of Taurocholate uptake in ASBT-expressing COS cellsMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Heinrich Heine University
Curated by ChEMBL
Heinrich Heine University
Curated by ChEMBL
Affinity DataEC50: 1.05E+5nMAssay Description:Agonist activity at human TGR5 Y89A mutant expressed in HEK293 cells assessed as rise in intracellular cAMP level incubated for 16 hrs by luciferase ...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Heinrich Heine University
Curated by ChEMBL
Heinrich Heine University
Curated by ChEMBL
Affinity DataEC50: 5.05E+4nMAssay Description:Agonist activity at wild type human TGR5 expressed in HEK293 cells assessed as rise in intracellular cAMP level incubated for 16 hrs by luciferase re...More data for this Ligand-Target Pair
Affinity DataKd: 1.00E+4nMAssay Description:Binding affinity to human pancreatic recombinant 1B PLA2 expressed in Escherichia coli by resonance energy transfer assay in presence of trimethyl-am...More data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Heinrich Heine University
Curated by ChEMBL
Heinrich Heine University
Curated by ChEMBL
Affinity DataEC50: 3.00E+4nMAssay Description:Agonist activity at human TGR5 expressed in CHO cells by luciferase assayMore data for this Ligand-Target Pair