BDBM50237288 CHEMBL4073198

SMILES COCCn1cc(NC(=O)c2csc(n2)-c2nncn2C(C)C)cn1

InChI Key InChIKey=NWXGFDVFXJMUDD-UHFFFAOYSA-N

Data  12 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50237288   

TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50237288(CHEMBL4073198)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50237288(CHEMBL4073198)
Affinity DataEC50:  60nMAssay Description:In vitro inhibition of porcine Dipeptidylpeptidase II.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50237288(CHEMBL4073198)
Affinity DataIC50:  60nMAssay Description:In vitro inhibition of porcine Dipeptidylpeptidase II.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50237288(CHEMBL4073198)
Affinity DataIC50: <2.00E+4nMAssay Description:Compound was tested for inhibitory activity against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 3(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50237288(CHEMBL4073198)
Affinity DataIC50: <2.00E+4nMAssay Description:Inhibition of recombinant human His-tagged EPHA3 cytoplasmic domain (569 to 976 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50237288(CHEMBL4073198)
Affinity DataIC50: <2.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ERBB4 cytoplasmic domain (708 to 993 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50237288(CHEMBL4073198)
Affinity DataIC50:  5.37E+3nMAssay Description:Inhibition of recombinant human GST-tagged ROCK1 catalytic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50237288(CHEMBL4073198)
Affinity DataIC50:  7.59E+3nMAssay Description:Inhibition of recombinant human GST-tagged MER cytoplasmic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50237288(CHEMBL4073198)
Affinity DataIC50:  794nMAssay Description:Inhibition of PRKAA1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50237288(CHEMBL4073198)
Affinity DataIC50:  617nMAssay Description:Inhibition of recombinant human GST-tagged RET cytoplasmic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50237288(CHEMBL4073198)
Affinity DataIC50: <2.00E+4nMAssay Description:Inhibition of recombinant human GST-tagged RON cytoplasmic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50237288(CHEMBL4073198)
Affinity DataIC50: <2.00E+4nMAssay Description:Inhibition of recombinant full length human GST-tagged ITK expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50237288(CHEMBL4073198)
Affinity DataIC50:  457nMAssay Description:Inhibition of recombinant full length human His-tagged GSK3B expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed