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BDBM50237867 CHEMBL258404::N-(5-(2,5-dioxoimidazolidin-1-yl)-1H-indazol-3-yl)-2-phenylacetamide

SMILES: Oc1c[nH]c(=O)n1-c1ccc2[nH]nc(NC(=O)Cc3ccccc3)c2c1

InChI Key: InChIKey=WIPVOTCWCILSOJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50237867   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cyclin-dependent kinase 2


(Homo sapiens (Human))
BDBM50237867
PNG
(CHEMBL258404 | N-(5-(2,5-dioxoimidazolidin-1-yl)-1...)
Show SMILES Oc1c[nH]c(=O)n1-c1ccc2[nH]nc(NC(=O)Cc3ccccc3)c2c1
Show InChI InChI=1S/C18H15N5O3/c24-15(8-11-4-2-1-3-5-11)20-17-13-9-12(6-7-14(13)21-22-17)23-16(25)10-19-18(23)26/h1-7,9-10,25H,8H2,(H,19,26)(H2,20,21,22,24)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Keimyung University

Curated by ChEMBL


Assay Description
Inhibition of CDK2


Bioorg Med Chem Lett 18: 2292-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.03.002
BindingDB Entry DOI: 10.7270/Q2QN66H5
More data for this
Ligand-Target Pair