BDBM50239391 2-Mercapto-Benzoic Acid::CHEBI:59124::THIOSALICYLIC ACID

SMILES OC(=O)c1ccccc1S

InChI Key InChIKey=NBOMNTLFRHMDEZ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

PDB links: 4 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50239391   

TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50239391(2-Mercapto-Benzoic Acid | CHEBI:59124 | THIOSALICY...)
Affinity DataEC50:  1.69E+4nMAssay Description:Substrate-dependent activation of HDAC8 (unknown origin) using FLUOR DE LYS as substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50239391(2-Mercapto-Benzoic Acid | CHEBI:59124 | THIOSALICY...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed