BDBM50239781 CHEMBL4066936

SMILES COC(=O)Nc1c(N)nc(nc1N)-c1nn(Cc2ccccc2F)c2ncc(F)cc12

InChI Key InChIKey=QZFHIXARHDBPBY-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50239781   

TargetCytochrome P450 1A2(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50239781(CHEMBL4066936)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human liver microsomes CYP1A2 using phenacetin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50239781(CHEMBL4066936)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human liver microsomes CYP3A4 using testosterone as substrate preincubated with compound followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2019
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50239781(CHEMBL4066936)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human liver microsomes CYP2C8 using amodiaquine as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2019
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50239781(CHEMBL4066936)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human liver microsomes CYP2A6 using coumarin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2019
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50239781(CHEMBL4066936)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human liver microsomes CYP2C19 using S-mephenytoin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2019
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50239781(CHEMBL4066936)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human liver microsomes CYP2C9 using diclofenac as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50239781(CHEMBL4066936)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human liver microsomes CYP3A4 using midazolam as substrate preincubated with compound followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50239781(CHEMBL4066936)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human liver microsomes CYP3A4 using midazolam as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50239781(CHEMBL4066936)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human liver microsomes CYP3A4 using testosterone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2019
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50239781(CHEMBL4066936)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human liver microsomes CYP2D6 using dextromethorphan as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2019
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50239781(CHEMBL4066936)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human liver microsomes CYP2B6 using bupropion as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2019
Entry Details Article
PubMed