BDBM50239857 CHEMBL4070745
SMILES COc1cc(NC(=O)NOCCCCCC(=O)NO)c2ncccc2c1
InChI Key InChIKey=CLGDSTJRIXLINL-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50239857
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by ChEMBL
Heinrich-Heine-Universit£T D£Sseldorf
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of recombinant full length human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected sf9 cells using Z-(Ac)Lys-AMC as subst...More data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by ChEMBL
Heinrich-Heine-Universit£T D£Sseldorf
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged/C-terminal His-tagged HDAC4 expressed in insect cells using Boc-K(Ac)-AMC as substrate by fluor...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by ChEMBL
Heinrich-Heine-Universit£T D£Sseldorf
Curated by ChEMBL
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of human HDAC8 using Z-L-Lys(epsilon-trifluoroacetyl)-AMC as substrate measured after 90 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by ChEMBL
Heinrich-Heine-Universit£T D£Sseldorf
Curated by ChEMBL
Affinity DataIC50: 6.10nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells Z-(Ac)Lys-AMC as substrate measur...More data for this Ligand-Target Pair