BDBM50240047 CHEBI:4724::Dyclonine

SMILES CCCCOc1ccc(cc1)C(=O)CCN2CCCCC2

InChI Key InChIKey=BZEWSEKUUPWQDQ-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50240047   

TargetAcetylcholinesterase(Human)
Prin. K. M. Kundnani College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50240047(CHEBI:4724 | Dyclonine | US20240358711, Compound D...)
Affinity DataIC50: 181nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Mouse)
Immunyx Pharma

US Patent
LigandPNGBDBM50240047(CHEBI:4724 | Dyclonine | US20240358711, Compound D...)
Affinity DataIC50: 2.00E+3nMAssay Description:A high-throughput screen was performed to find molecules that inhibit ROS production by neutrophils. Extracted human neutrophils were purified and ke...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Immunyx Pharma

US Patent
LigandPNGBDBM50240047(CHEBI:4724 | Dyclonine | US20240358711, Compound D...)
Affinity DataIC50: 2.50E+3nMAssay Description:A high-throughput screen was performed to find molecules that inhibit ROS production by neutrophils. Extracted human neutrophils were purified and ke...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily V member 3(Mouse)
Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240047(CHEBI:4724 | Dyclonine | US20240358711, Compound D...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of mouse TRPV3 expressed in HEK293 cells assessed as reduction in 2-APB evoked current at -60 mV holding potential by whole-cell patch cla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50240047(CHEBI:4724 | Dyclonine | US20240358711, Compound D...)
Affinity DataIC50: 2.75E+5nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2019
Entry Details Article
PubMed