BDBM50240175 CHEMBL4071714::US9962398, Compound MST-146

SMILES NS(=O)(=O)c1ccc(NC(=O)Nc2ccc(cc2Cl)C(F)(F)F)cc1

InChI Key InChIKey=SELVWAYDIKAGAI-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50240175   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Welichem Biotech

US Patent
LigandPNGBDBM50240175(CHEMBL4071714 | US9962398, Compound MST-146)
Affinity DataKi:  0.970nMAssay Description: CA INHIBITION DATA WITH UREIDOSUBSTITUTED SULFONAMIDES More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Welichem Biotech

US Patent
LigandPNGBDBM50240175(CHEMBL4071714 | US9962398, Compound MST-146)
Affinity DataKi:  0.970nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stoppe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50240175(CHEMBL4071714 | US9962398, Compound MST-146)
Affinity DataKi:  8.20nMAssay Description:Binding affinity was determined based on the displacement of [125]r-ANF (99-126) from binding sites on bovine adrenal zona glomerulosa cell membranes...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50240175(CHEMBL4071714 | US9962398, Compound MST-146)
Affinity DataKi:  8.20nMAssay Description: CA INHIBITION DATA WITH UREIDOSUBSTITUTED SULFONAMIDES More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Welichem Biotech

US Patent
LigandPNGBDBM50240175(CHEMBL4071714 | US9962398, Compound MST-146)
Affinity DataKi:  8.40nMAssay Description: CA INHIBITION DATA WITH UREIDOSUBSTITUTED SULFONAMIDES More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Welichem Biotech

US Patent
LigandPNGBDBM50240175(CHEMBL4071714 | US9962398, Compound MST-146)
Affinity DataKi:  8.40nMAssay Description:Inhibitory activity against dog gastric proton-pump enzyme H+/K+ ATPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Welichem Biotech

US Patent
LigandPNGBDBM50240175(CHEMBL4071714 | US9962398, Compound MST-146)
Affinity DataKi:  192nMAssay Description: CA INHIBITION DATA WITH UREIDOSUBSTITUTED SULFONAMIDES More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Welichem Biotech

US Patent
LigandPNGBDBM50240175(CHEMBL4071714 | US9962398, Compound MST-146)
Affinity DataKi:  192nMAssay Description:Inhibitory activity against dog gastric proton-pump enzyme H+/K+ ATPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed